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  Section: Biotechnology Methods » Cell Biology and Genetics
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Observation of Mutants in Drosophila Melanogaster

Cell Biology and Genetics
  Cell Cycles
  Meiosis in Flower Buds of Allium Cepa-Acetocarmine Stain
  Meiosis in Grasshopper Testis (Poecilocerus Pictus)
  Mitosis in Onion Root Tip (Allium Cepa)
  Differential Staining of Blood
  Buccal Epithelial Smear and Barr Body
  Vital Staining of DNA and RNA in Paramecium
  Induction of Polyploidy
  Mounting of Genitalia in Drosophila Melanogaster
  Mounting of Genitalia in the Silk Moth Bombyx Mori
  Mounting of the Sex Comb in Drosophila Melanogaster
  Mounting of the Mouth Parts of the Mosquito
  Normal Human Karyotyping
  Black and White Film Development and Printing for Karyotype Analysis
  Study of Drumsticks in the Neutrophils of Females
  Study of the Malaria Parasite
  Vital Staining of DNA and RNA in Paramecium
  Sex-Linked Inheritance in Drosophila Melanogaster
  Preparation of Somatic Chromosomes from Rat Bone Marrow
  Chromosomal Aberrations
  Study of Phenocopy
  Study of Mendelian Traits
  Estimation of Number of Erythrocytes [RBC] in Human Blood
  Estimation of Number of Leucocytes (WBC) in Human Blood
  Culturing Techniques and Handling of Flies
  Life Cycle of the Mosquito (Culex Pipiens)
  Life Cycle of the Silkworm (Bombyx Mori)
  Vital Staining of Earthworm Ovary
  Culturing and Observation of Paramecium
  Culturing and Staining of E.coli (Gram’s Staining)
  Breeding Experiments in Drosophila Melanogaster
  Preparation of Salivary Gland Chromosomes
  Observation of Mutants in Drosophila Melanogaster
  ABO Blood Grouping and Rh Factor in Humans
  Determination of Blood Group and Rh Factor
  Demonstration of the Law of Independent Assortment
  Demonstration of Law of Segregation

Mutations are heritable changes in the genetic material. A mutant phenotype is a heritable deviant from the standard phenotype, and caused due to mutation. A mutation is said to be dominant if it expresses in the heterozygous condition. A mutation is said to be recessive if it requires a homozygous state for its expression.

A recessive mutation on the X chromosome in male is expressed since the Y chromo-some does not carry the corresponding allele, and this is referred to as the hemizygous condition. However, the same recessive mutation on X chromosome needs the homozygous condition in the female for expression.

Yellow Body
Symbol : y
Location : 1-0.0
The body is yellow with hair and bristles that are brownish, with yellow tips.
The wings, hairs, and veins are yellow. The larval mouth parts are yellow to brown.

Ebony Body
Symbol : e
Location : 3-30.7
The body is black in adults. Larvae show darkened spiracle sheath compared
to wild-type larvae.

Vestigial Wing
Symbol: vg
Location: 2-67.0
Wings and balancers are greatly reduced.

Curly Wing
Symbol: Cy
Location: 2-6.1
Associated with curly inversion on the left arm (2L) of the second chromosome.
Wings are strongly curved upward and forward. The homozygote is lethal.

White Eye
Symbol: w
Location: 1-1.5
White eyes, colorless ocelli, Malphigian tubules and testis.

Sepia Eye
Symbol: Se
Location: 3-2.6
Brownish-red eyes that darken to sepia and finally to black. The ocelli are wild type
Brown Eye
Symbol: bw
Location: 2-104.5
Brownish-wine eyes that become purplish with age.


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